National Center for Mariculture Hanna Rosenfeld hanna@ocean.org.il Tel: 08 – 6361471 Scientist Ph.D. 2001, Tel Aviv University, Israel At IOLR since 1992

Research interests:
Studies on fish reproductive physiology including mechanisms controlling sex differentiation, environmental and hormonal cues that initiate and regulate sexual maturity, and in vivo/ in vitro procedures promoting gamete maturation and fertilization. Focus on developing methodologies and technologies for an efficient broodstock management of various finfish, i.e. seabream, sea bass, mullet, grouper & bluefin tuna.

Selected publications:
Aizen, J., Meiri, I., Tzchori, I., Levavi-Sivan, B. and Rosenfeld, H. Enhancing spawning in the grey mullet (Mugil cephalus) by removal of dopaminergic inhibition. Gen. Comp. Endocrinol (in press).

Levavi-Sivan, B., Safarian, H., Rosenfeld, H., Elizur, A. and Avitan, A. (2004). Regulation of Gonadotropin-Releasing Hormone (GnRH) Receptor Gene Expression in Tilapia: Effect of GnRH and Dopamine. Biol. Reprod. 70:1545-1551.

Rosenfeld, H., Klenke, U., Gordin, H. and Zohar, Y. (2003). Preliminary study of the key hormones regulating reproduction in the bluefin tuna (BFT): the brain gonadotropin- releasing hormones (GnRHs) and the pituitary gonadotropins, FSH and LH. Cah. Options Medit. 60:177-181.

Yaron, Z., Gur, G., Melamed, P., Rosenfeld, H., Elizur, A. and Levavi-Sivan, B. (2002). Regulation of fish gonadotropin. Int. Rev. Cytol. 225:131-185.

Rosenfeld, H., Levavi-Sivan, B., Gur, G., Melamed, P., Meiri, I., Yaron, Z. and Eilzur, A. (2001). Characterization of the tilapia FSH b gene and analysis of its 5` flanking region. Comp. Biochem. Physiol. 129B:389-398.

Gur, G., Rosenfeld, H., Melamed, P., Meiri, I., Elizur, A. and Yaron, Z. (2001). Tilapia glycoprotein hormone a- subunit: cDNA cloning and hypothalamic regulation. Mol. Cell. Endocrinol. 182:49-60.

Yaron, Z., Gur, G., Melamed, P., Rosenfeld, H., Levavi-Sivan, B. and Elizur, A. (2001). Regulation of gonadotropin subunit genes in tilapia. Comp. Biochem. Physiol. 129B:489-502.

Melamed, P., Rosenfeld, H., Elizur, A. and Yaron, Z. (1998). Endocrine regulation of gonadotropin and growth hormone gene transcription in fish. Comp. Biochem. Physiol. C-Pharmacol. Toxicol. Endocrinol. 119:325-338.

Rosenfeld, H., Levavi-Sivan, B., Melamed, P., Yaron, Z. and Elizur, A. (1998). The genes encoding the GtHbsubunits in tilapia. Trends Comp. Endocrinol. Neurobiol. Ann. N. Y. Acad. Sci. 839:455-457.

Rosenfeld, H., Levavi-Sivan, B., Melamed, P., Yaron, Z. and Elizur, A. (1997). The GTH b subunits of tilapia: gene cloning and expression. Fish Physiol. Biochem. 17:85-92.