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דף הבית מכוני מחקר ותשתיות המעבדה לחקר הכנרת חוקרי המעבדה פלג אסטרחן

Yigal Alon Kinneret Limnological Laboratory

Peleg Astrahan

peleg.astrahan@ocean.org.il
Tel: 04 – 6721444 ext. 220

Senior Scientist

Ph.D. 2010 Hebrew University, Israel.
At IOLR since 2013

Research interests:
Marine and freshwater organic matter chemistry.
Among the studied topics are the type, distribution and fate of molecules such as polysaccharides, dissolved organic nitrogen, oil degradation products and pesticides. In addition to these topics, I study the unique ecosystem of the microlayer which is the contact layer between the water and the atmosphere.

Selected publications:
Alhadeff, R., Assa, D., Astrahan, P., Krugliak, M., Arkin, I.T. computational and experimental analysis of drug binding to the influenza m2 channel. biochimica et biophysica acta (bba) biomembranes vol. 1838, (4): 1068-1073 (2014).

Leonov, H., Astrahan, P., Krugliak, M., Arkin, I.T. How Do Aminoadamantanes Block the Influenza M2 Channel, and How Does Resistance Develop? Journal of the American Chemical Society (JACS) Vol. 133, (25): 9627-9948 (2011).

Astrahan, P., Tene, F.R., Bennett, E.R., Krugliak, M., Gilon, C., Arkin, I.T. Quantitative Analysis of Influenza M2 Channel Blockers. Biochimica et Biophysica Acta (BBA) Vol. 1808(1): 394-8 (2011).

Astrahan, P., Arkin, I.T Resistance Characteristics of Influenza to Amino-Adamantyls. . Biochimica et Biophysica Acta (BBA) Vol. 1808: 547-553 (2011).

Shmeeda, H., Mak, L., Tzemach, D., Astrahan, P., Tarshish, M., and Gabizon, A. Molecular Cancer
Intracellular Uptake and Intracavitary Targeting of Folate-Conjugated Liposomes in a Mouse Lymphoma Model With Up-Regulated Folate Receptors. Therapeutics (5): 818-824 (2006).

Astrahan, P., Kass, I., Cooper, M.A., Arkin, I.T. A Novel Method of Resistance for Influenza Against a Channel-Blocking Anti-Viral Drug Proteins: Structure, Function and Bioinformatics (55): 251-257 2004.
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